Anti-Bax Monoclonal Antibody
产品名称: Anti-Bax Monoclonal Antibody
英文名称: Anti-Bax Monoclonal Antibody
产品编号: K001435M
产品价格: null
产品产地: 北京
品牌商标: solarbio
更新时间: 2025-12-22T13:21:18
使用范围: WB
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市北京经济技术开发区环科中路16号26幢3层301
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- 所在区域 : 北京
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Anti-Bax Monoclonal Antibody
品牌:solarbio | 货号:K001435M
| 英文名称 | Anti-Bax Monoclonal Antibody |
|---|---|
| 别名 | BCL2L4 |
| 应用 | WB |
| 稀释比例 | WB 1:1000. |
| 交叉反应 | Human Monkey |
| 蛋白分子量 | 20kDa |
| Gene ID | 581 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG2a |
| 免疫原 | Purified recombinant human Bax protein fragments expressed in E.coli |
| 性状 | 液体 |
| Public Immunogen Range | Purified recombinant human Bax protein fragments expressed in E.coli |
| Subcellular Locations | Cytoplasm Cytoplasm Mitochondrion membrane Single-pass membrane protein |
| Swiss Prot | Q07812 |
| 克隆号 | 2B12-G6-H6 |
| 克隆类型 | Monoclonal Antibody |
| 背景资料 | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. (provided by RefSeq, Jul 2008). |
