Recombinant Biotinylated Cynomolgus TL1A Protein,His-Avi Tag
产品名称： Recombinant Biotinylated Cynomolgus TL1A Protein,His-Avi Tag
英文名称： Recombinant Biotinylated Cynomolgus TL1A Protein,His-Avi Tag
产品编号： 93078ES
产品价格： 询价
产品产地： Yeasen
品牌商标： Yeasen
更新时间： 2025-08-21T10:37:58
使用范围： null
翌圣生物科技（上海）股份有限公司
- 联系人 : 李自转
- 地址 : 上海市浦东新区天雄路166弄一号楼三层南单元
- 邮编 : 200030
- 所在区域 : 上海
- 电话 : 139****5640 点击查看
- 传真 : 点击查看
- 邮箱 : lizizhuan@yeasen.com
- 二维码 : 点击查看
产品介绍
Tumor necrosis factor (TNF)-like cytokine 1A (TL1A) is a member of the TNF superfamily of proteins (TNFSF15), which signals through association with death domain receptor 3 (DR3). Decoy receptor 3 (DcR3) competes with DR3 for TL1A binding and inhibits functional signaling. These proteins are significantly upregulated in inflamed intestinal tissues, and their pathogenetic importance forinflammatory bowel disease (IBD) is suggested by accumulating evidence. TL1A/DR3 induce costimulatory signals to activated lymphocytes, including the gut-specific populations of CD4+CD161+ and CD4+CCR9+ cells, affecting all major effector pathways and inducing the mucosal upregulation of Th1, Th2, and Th17 factors.
产品性质
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产品别称
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VEGI, TNFSF15
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种属
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Cynomolgus
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表达序列
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Leu 72 - Leu 251
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Accession
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F6S8F9-1
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标签
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N-His-Avi Tag
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表达系统
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HEK293
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分子量
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The protein has a predicted MW of 22.3 kDa
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纯度
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> 95% as determined by SDS-PAGE
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内毒素
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< 1.0 EU per μg by the LAL method.
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制剂
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Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
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外观
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Liquid
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生物活性
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ELISA: Biotinylated Cynomolgus TL1A Protein; His-Avi Tag was immobilized at 1 μg/ml (100 μL/well) on streptavidin precoated. Increasing concentrations of Anti-HumanTNFSF15(TL1A) hIgG1 Antibody were added.
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产品特色
高纯度、高活性、低内毒素、高批间一致性
应用案例
SDS-PAGE
Figure 1.On SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Bioactivity-ELISA
Figure 2. Biotinylated Cynomolgus TL1A Protein; His-Avi Tag was immobilized at 1 μg/ml (100 μL/well) on streptavidin precoated. Increasing concentrations of Anti-HumanTNFSF15(TL1A) hIgG1 Antibody were added.
存储条件
-85 ~ -65℃保存，收到货之日起，6个月有效期。避免反复冻融，建议等分分装为一次实验使用量，分装后，-80℃冻存。